Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1992 Sep;89(3):419-22.
doi: 10.1111/j.1365-2249.1992.tb06973.x.

Hepatitis C: a possible etiology for cryoglobulinaemia type II

A Pechère-Bertschi  1 , L Perrin, P de Saussure, J J Widmann, E Giostra, J A Schifferli
Affiliations

Hepatitis C: a possible etiology for cryoglobulinaemia type II

A Pechère-Bertschi et al. Clin Exp Immunol. 1992 Sep.

Abstract

Out of 15 successive patients with mixed essential cryoglobulinaemia type II (monoclonal IgM kappa/IgG), 13 had serological evidence for hepatitis C infection as shown by specific enzyme immunoassays and immunoblot. RNA was purified from the serum of seven patients and hepatitis C sequences were identified in five following reverse transcription and DNA amplification. The liver histology showed chronic active hepatitis with or without cirrhosis in the 12 patients with hepatitis C who had a liver biopsy. The two patients without serological evidence of hepatitis C suffered from haematological malignancies. Hepatitis C may be a major etiological agent of cryoglobulinaemia type II.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Ann Intern Med. 1977 Sep;87(3):287-92 - PubMed
    1. Clin Exp Immunol. 1992 Mar;87(3):352-6 - PubMed
    1. Clin Exp Rheumatol. 1992 Jan-Feb;10(1):103-4 - PubMed
    1. Arthritis Rheum. 1991 Dec;34(12):1606-10 - PubMed
    1. Jpn J Exp Med. 1990 Jun;60(3):167-77 - PubMed

Publication types

MeSH terms