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Case Reports
. 1992 Jul;83(7):680-3.
doi: 10.1111/j.1349-7006.1992.tb01965.x.

CD7 expression in malignant pleural mesothelioma

S Hibi  1 , Y Kataoka, N Fujita, H Okabe, K Yoshikawa, M Seto, R Ueda, S Imashuku
Affiliations
Case Reports

CD7 expression in malignant pleural mesothelioma

S Hibi et al. Jpn J Cancer Res. 1992 Jul.

Abstract

CD7 antigen was found to be expressed on malignant mesothelioma arising from the right pleura in a 15-year-old girl not only by immunostaining using monoclonal antibodies, but also by Northern blot analysis. The level of expression in this tumor was comparable to those in T-cell lines, Jurkat and CCRF-CEM. Cytogenetic analysis of the tumor showed hypodiploidy (n = 43). CD7 has been regarded as one of the hematopoietic cell markers selectively expressed on the majority of T cells and multipotential stem cells. To our knowledge, this is the first report of a non-hematopoietic tumor expressing CD7.

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