Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1992 Aug;106(4):764-5.
doi: 10.1111/j.1476-5381.1992.tb14409.x.

Ca2+ release from isolated sarcoplasmic reticulum of guinea-pig psoas muscle induced by K(+)-channel blockers

Y Ishida  1 , H Honda, T X Watanabe
Affiliations

Ca2+ release from isolated sarcoplasmic reticulum of guinea-pig psoas muscle induced by K(+)-channel blockers

Y Ishida et al. Br J Pharmacol. 1992 Aug.

Abstract

A Ca(2+)-sensitive electrode was used to measure the Ca2+ concentration of the medium containing the heavy fraction of the fragmented sarcoplasmic reticulum (SR) prepared from guinea-pig psoas muscle. Among K(+)-channel blockers tested, 4-aminopyridine (4-AP), tetraethylammonium (TEA) and charybdotoxin elicited Ca2+ release from the SR, but apamin and glibenclamide did not. These results suggest that a reduction of SR K+ conductance leads to Ca2+ release from the SR.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. J Biol Chem. 1983 Aug 25;258(16):9662-8 - PubMed
    1. Biochem Biophys Res Commun. 1990 Jul 31;170(2):684-90 - PubMed
    1. Pflugers Arch. 1991 Feb;417(6):651-3 - PubMed
    1. J Pharmacol Exp Ther. 1988 Aug;246(2):667-73 - PubMed
    1. Nature. 1985 Jan 24-30;313(6000):316-8 - PubMed