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Case Reports
. 1992;421(3):271-5.
doi: 10.1007/BF01611185.

Nodular sclerosing Hodgkin's disease and large cell lymphoma. Immunophenotypic characterization of a composite case

M Paulli  1 , R Rosso, S Kindl, E Boveri, M Sirchi, A De Medici, R Invernizzi, U Magrini
Affiliations
Case Reports

Nodular sclerosing Hodgkin's disease and large cell lymphoma. Immunophenotypic characterization of a composite case

M Paulli et al. Virchows Arch A Pathol Anat Histopathol. 1992.

Abstract

Composite lymphomas have rarely been reported in Hodgkin's disease (HD), except in the lymphocyte predominance sub-type, and immunohistochemical investigations have been performed in only few cases. We describe the histological and immunophenotypical findings in a case of composite nodular sclerosing HD and high-grade, large cell non-Hodgkin's lymphoma (NHL). In our case HD and NHL cells displayed striking morphological and immunophenotypical divergence, suggesting a lack of correlation between the two neoplasms.

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