The conglutination phenomenon. XII. Immuno-conglutinin in experimental infections of laboratory animals

Abstract

Immuno-conglutinin has been stimulated in rabbits after infection with Listeria monocytogenes, Salmonella typhi-murium and other bacterial species. Infection of rabbits with Western Equine Encephalomyelitis, Hammon Reeves, Murray Valley Encephalitis and Aedes trivittatus viruses also stimulated the production of this substance. The most marked immuno-conglutinin response followed infection of rabbits with Trypanosma brucei.

Rickettsia burneti infection in guinea pigs produced a biphasic immuno-conglutinin response, the first phase being coincident with the rise of antibodies to the Phase II antigen and the second phase with the retarded rise of antibodies to the Phase I antigen.

In mice also, the immuno-conglutinin level was raised following infection with Escherichia coli, Salmonella typhi-murium and other bacterial species.