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Review
. 1992 Apr;2(2):199-204.
doi: 10.1016/s0959-437x(05)80274-6.

The CREB family of transcription activators

P K Brindle  1 , M R Montminy
Affiliations
Review

The CREB family of transcription activators

P K Brindle et al. Curr Opin Genet Dev. 1992 Apr.

Abstract

A diverse family of transcription factors bind to the cAMP-response elements found in a variety of mammalian and viral gene promoters. One of the members of this family, CREB, is being intensively studied so as to elucidate the mechanisms by which second messenger signal transduction pathways act to positively and negatively regulate transcription.

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