doi: 10.1084/jem.115.6.1173.
Effects of chronia excess salt ingestion. Evidence that genetic factors play an important role in susceptibility to experimental hypertension
- PMID: 13883089
- PMCID: PMC2137393
- DOI: 10.1084/jem.115.6.1173
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Effects of chronia excess salt ingestion. Evidence that genetic factors play an important role in susceptibility to experimental hypertension
J Exp Med.
.
Abstract
Using the genetic technique of selective inbreeding, it has been possible to quickly develop two statistically separable populations from one unselected strain of Sprague-Dawley rats. One of these is very sensitive, the other very resistant, to the development of experimental hypertension from a high salt diet. It was suggested that similar genetic factors operate in man.
Comment in
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Lewis Dahl and the genetics of salt-induced hypertension.J Exp Med. 2007 Jul 9;204(7):1507. doi: 10.1084/jem.2047fta. J Exp Med. 2007. PMID: 17650543 Free PMC article.
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