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. 1962 Jun 1;115(6):1173-90.
doi: 10.1084/jem.115.6.1173.

Effects of chronia excess salt ingestion. Evidence that genetic factors play an important role in susceptibility to experimental hypertension

L K DAHL, M HEINE, L TASSINARI

Effects of chronia excess salt ingestion. Evidence that genetic factors play an important role in susceptibility to experimental hypertension

L K DAHL et al. J Exp Med. .

Abstract

Using the genetic technique of selective inbreeding, it has been possible to quickly develop two statistically separable populations from one unselected strain of Sprague-Dawley rats. One of these is very sensitive, the other very resistant, to the development of experimental hypertension from a high salt diet. It was suggested that similar genetic factors operate in man.

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