Review
doi: 10.1016/0167-5699(92)90008-U.
The origin and function of tumor-associated macrophages
Affiliations
- PMID: 1388654
- DOI: 10.1016/0167-5699(92)90008-U
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Review
The origin and function of tumor-associated macrophages
Immunol Today.
1992 Jul.
Abstract
Tumor-associated macrophages (TAM) have a complex relationship with the neoplastic cells of the tumor. On the one hand, the two cell types produce reciprocal growth factors and may be considered to have a symbiotic relationship. On the other hand, TAM can be activated to inhibit tumor growth and destroy neoplastic cells. Here, Alberto Mantovani and colleagues describe this delicate balance and the prospects for its therapeutic manipulation.
Comment in
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Chemotactic factors, passive invasion and metastasis of cancer cells.Immunol Today. 1992 Nov;13(11):463-4. doi: 10.1016/0167-5699(92)90079-M. Immunol Today. 1992. PMID: 1298279 No abstract available.
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Janus-faced tumor-associated macrophages.Immunol Today. 1993 Mar;14(3):142-3. doi: 10.1016/0167-5699(93)90220-F. Immunol Today. 1993. PMID: 8466631 No abstract available.
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