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Review
. 1992 Aug;4(4):396-400.
doi: 10.1016/s0952-7915(06)80029-4.

Heat-shock proteins: immunity and autoimmunity

D B Young  1
Affiliations
Review

Heat-shock proteins: immunity and autoimmunity

D B Young. Curr Opin Immunol. 1992 Aug.

Abstract

Antigens from a wide variety of pathogens have been identified as members of conserved heat-shock protein families, sharing upwards of 50% amino acid identity with corresponding host-cell proteins. Analysis of the responses to these conserved antigens may provide insights into regulation of the immune system during infection and autoimmunity.

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