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. 1992 Sep 24;1132(2):225-7.
doi: 10.1016/0167-4781(92)90019-v.

cDNA sequence for rat dermatan sulfate proteoglycan-II (decorin)

S R Abramson  1 , J F Woessner Jr
Affiliations

cDNA sequence for rat dermatan sulfate proteoglycan-II (decorin)

S R Abramson et al. Biochim Biophys Acta. .

Abstract

A cDNA clone for dermatan sulfate proteoglycan-II, or decorin, has been isolated from a rat uterus library and sequenced. The cDNA and deduced amino acid sequences are 79 and 77% identical to the previously reported human and bovine sequences, respectively. The rat protein contains potential attachment sites for two glycosaminoglycan chains and four N-linked oligosaccharides, six conserved cysteine residues and multiple repeats of a leucine-rich sequence, LXXLXLXXNXL/I. Overlapping the C-end of one of these repeats is an NKISK sequence, which has been implicated in binding to fibronectin.

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