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Clinical Trial
. 1992 Sep;65(3):121-3.
doi: 10.1007/BF01695810.

All-trans retinoic acid in acute promyelocytic leukemia: preliminary results in Cuba

P Hernández  1 , J Carnot, E Dorticós, E Espinosa, A González, I Rodríguez
Affiliations
Clinical Trial

All-trans retinoic acid in acute promyelocytic leukemia: preliminary results in Cuba

P Hernández et al. Ann Hematol. 1992 Sep.

Abstract

Seven patients with acute promyelocytic leukemia (APL) were treated with all-trans retinoic acid (ATRA). Five (71.4%) achieved complete remission (CR). Most side effects were transient and well tolerated. Hyperleukocytosis was the major adverse effect. These observations confirm the efficacy of ATRA for inducing CR in APL.

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