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. 1992 Sep;65(3):138-42.
doi: 10.1007/BF01695814.

Histoplasmosis in hairy cell leukemia: case report and review of the literature

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Histoplasmosis in hairy cell leukemia: case report and review of the literature

E Weeks et al. Ann Hematol. 1992 Sep.

Abstract

Progressive disseminated histoplasmosis (PDH) has been described in only six patients with hairy cell leukemia (HCL). Herein we describe an additional patient with HCL and disseminated histoplasmosis. Additionally, we note that three of seven cases of disseminated histoplasmosis and HCL have occurred in East Texas. PDH is to be suspected in febrile HCL patients in an endemic area who fail to respond to antibacterial therapy. We emphasize that serologic studies are useful in the diagnosis of PDH in HCL patients, and these patients respond well to therapy.

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