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. 1962 Feb:103:219-29.
doi: 10.1016/0002-9610(62)90491-9.

Homotransplantation of multiple visceral organs

T E STARZL, H A KAUPP Jr, D R BROCK, G W BUTZ Jr, J W LINMAN

Homotransplantation of multiple visceral organs

T E STARZL et al. Am J Surg. 1962 Feb.
No abstract available

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Figures

Fig. 1
Fig. 1
Schematic view of the transplanted tissues and their anatomic relation to the host. The grafted tissues are not shaded.
Fig. 2
Fig. 2
Addition of portacaval shunt to operation depicted in Figure 1.
Fig. 3
Fig. 3
Abdominal roentgenogram of Dog No. 18 on the sixth postoperative day. Dog had been on oral intake for four days.
Fig. 4
Fig. 4
Development of chemical jaundice with rise in alkaline phosphatase, seen in three of the five long-surviving dogs.
Fig. 5
Fig. 5
Absence of jaundice in two of the five long-surviving dogs. Note rise in alkaline phosphatase.
Fig. 6
Fig. 6
Fasting blood sugars in the five long-surviving dogs. Note usual absence of pronounced hypoglycemia.
Fig. 7
Fig. 7
Liver after nine days, from Dog No. 18, in which jaundice did not develop. A, magnification × 65; B, magnification × 350.
Fig. 8
Fig. 8
Liver after seven days, from Dog No. 4, in which jaundice developed. A, magnification × 65; B, magnification × 350.
Fig. 9
Fig. 9
Donor spleen, after nine days, from Dog No. 19. A, magnification × 65; B, magnification × 350.
Fig. 10
Fig. 10
Donor lymph node from mesentery of graft in Dog No. 26. Animal lived five and a half days. A, magnification × 30; B, magnification × 600.
Fig. 11
Fig. 11
Small intestine of Dog No. 4, seven days after transplantation (magnification × 18). Note congestion, edema and superficial slough.
Fig. 12
Fig. 12
Duodenal ulcer in Dog No. 18, after nine days (magnification × 25).
Fig. 13
Fig. 13
A, bone marrow from normal dog showing active granulopoiesis and erythropoiesis (magnification × 900). B, marrow from Dog No. 26, showing a cellular specimen with extensive replacement of normal myeloid elements by a relative and absolute increase in lymphocytes, reticulum cells and plasma cells (magnification × 900).
Fig. 14
Fig. 14
Lung from Dog No. 18, nine days after visceral transplantation (magnification × 350). Note pulmonary edema and proliferative thickening of alveolar septa.
Fig. 15
Fig. 15
Recipient lymph node from mediastinum of Dog No. 36 after six days. A, magnification × 30; B, magnification × 600.
Fig. 16
Fig. 16
State of denervation of multiple organ graft.
See this image and copyright information in PMC

References

    1. Berger RL, Lium R. Abdominal post-ganglionic sympathectomy: a method for the production of an ulcerative colitis-like state in dogs. Ann Surg. 1960;152:266. - PMC - PubMed
    1. Billingham RE. Reactions of grafts against their hosts. Science. 1959;130:947. - PubMed
    1. Goodrich EO, Welch HF, Nelson JA, Beecher TS, Welch CS. Homotransplantation of the canine liver. Surgery. 1956;39:244. - PubMed
    1. Kaupp HA, Jr, Starzl TE. The use of an external by-pass during experimental total hepatectomy. Surgery. 1960;48:330. - PMC - PubMed
    1. Lillehei CW, Wangensteen OH. Effect of celiac ganglionectomy upon experimental peptic ulcer formation. Proc Soc Exper Biol & Med. 1948;68:369. - PubMed

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