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. 1962 Jul;45(6):1099-115.
doi: 10.1085/jgp.45.6.1099.

Identification of active membrane areas in the giant neuron of Aplysia

L TAUC

Identification of active membrane areas in the giant neuron of Aplysia

L TAUC. J Gen Physiol. 1962 Jul.

Abstract

Intracellular and extracellular potentials were simultaneously recorded from the soma and different parts of the axon of the giant cell of Aplysia. Evidence was obtained that for all modes of stimulation the spike originates in the axon at some distance from the cell body. The conduction of the spike is blocked at a distance of 200 to 300 micro from the soma for the antidromic spike, closer to the soma for an orthodromic spike. This event is recorded in the soma as a small or A spike. After some delay, a spike is initiated in the resting part of the axon and in the axon hillock; the soma is invaded only afterwards. The response of these three parts of the neuron is recorded in the soma as the big or S spike.

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