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. 1963 Apr 26;140(3565):388-9.
doi: 10.1126/science.140.3565.388.

Tryptophan- and indole-excreting bacterial mutants

P G LIM, R I MATELES

Tryptophan- and indole-excreting bacterial mutants

P G LIM et al. Science. .

Abstract

Prototrophic mutants of Escherichia coli capable of producing indole and tryptophan were obtained by selecting for resistance to antimetabolites. An anthranilic acid auxotroph grown under conditions which would derepress the tryptophan synthetase system would also accumulate substantial quantities of L-tryptophan.

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