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. 1977 Jan;7(1):38-40.
doi: 10.1002/eji.1830070109.

Selective activation of human suppressor cells by a nonproliferative stimulus

P M Sondel, M W Jacobson, F H Bach

Selective activation of human suppressor cells by a nonproliferative stimulus

P M Sondel et al. Eur J Immunol. 1977 Jan.

Abstract

The eliciting of suppressor cell activity by heat-treated stimulating cells demonstrates that suppression can be induced by an antigenic but non-effective mixed lymphocyte culture (MLC) stimulus in vitro. Simultaneous or prior MLC or cytotoxic T lymphocyte activity is not required for alloantigen-induced suppressor cell activation.

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