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. 1992 Sep 15;75(2-3):179-85.
doi: 10.1016/0378-1097(92)90400-i.

Characterisation of a novel repetitive DNA sequence from Mycobacterium bovis

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Characterisation of a novel repetitive DNA sequence from Mycobacterium bovis

T J Doran et al. FEMS Microbiol Lett. .

Abstract

We report characterisation of three copies of a novel repeat sequence isolated from a Mycobacterium bovis genomic library. The repeat occurs within open reading frames, potentially encoding a conserved tandem array of a pentapeptide sequence with the consensus X-Gly-Asn-X-Gly. The tandem array is present up to five times in M. bovis and it is proposed that they may occur in a family of genes expressing functionally related proteins. We postulate that these proteins may play a role in binding of M. bovis to host cell receptors.

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