Structure of the rainbow trout metallothionein A gene
- PMID: 1398141
- DOI: 10.1016/0378-1119(92)90105-x
Structure of the rainbow trout metallothionein A gene
Abstract
To investigate the regulation of metallothionein-encoding genes in fish, we have isolated and sequenced the rainbow trout metallothionein-A-encoding gene (tMT-A) by polymerase chain reaction. This gene spans about 1.1 kb, consists of three exons and two introns, and has an A+T-rich 5'-region which contains a TATAAA signal, and two metal responsive elements (MREs). The transcription start point is centered around an A residue 81 nt upstream of the ATG codon.
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