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. 1977 Apr;53(2):115-7.
doi: 10.1136/sti.53.2.115.

Treatment of uncomplicated gonorrhoea with spectinomycin hydrochloride (Trobicin)

I A Porter, H W Rutherford

Treatment of uncomplicated gonorrhoea with spectinomycin hydrochloride (Trobicin)

I A Porter et al. Br J Vener Dis. 1977 Apr.

Abstract

110 patients with uncomplicated gonococcal urethritis were treated with 2 g spectinomycin (Trobicin) intramuscularly. Seventy-five patients were available for follow-up and there was only one treatment failure, giving a cure rate of 98-6%. Of the 99 gonococcal isolates, 59 were sensitive to 5 microng/ml of spectinomycin or less and 40 were sensitive to 10 microng/ml. In a small sample of patients 2 g spectinomycin intramuscularly produced a serum concentration averaging 100 microng/ml after one hour.

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References

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