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. 1963 Jul;16(4):332-6.
doi: 10.1136/jcp.16.4.332.

AGGLUTINATION REACTIONS OF HUMAN LEUCOCYTES

J SCHULZ, H MULLER

AGGLUTINATION REACTIONS OF HUMAN LEUCOCYTES

J SCHULZ et al. J Clin Pathol. 1963 Jul.

Abstract

Agglutination tests with various sera and leucocytes from 58 leukaemic patients and 61 patients without leukaemia are reported. The agglutination of white blood cells by guinea-pig serum is of limited value in the diagnosis of leukaemia, though the test may be helpful in distinguishing leukaemia from other lymphomatous disorders.Leuco-autoagglutinins were demonstrated more frequently than expected. Eleven leukaemic and six non-leukaemic sera agglutinated autologous leucocytes. White blood cell agglutinins showed no apparent relationship to maturity or numbers of circulating leucocytes or to previous blood transfusions, x-irradiation, or therapy with antimetabolites.

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References

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    1. Nature. 1961 Sep 9;191:1110-1 - PubMed
    1. J Exp Med. 1953 Dec;98(6):565-82 - PubMed
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