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. 1977 Apr;16(4):629-36.

Effects of serotonergic drugs on methaqualone-induced hypothermia

  • PMID: 140451

Effects of serotonergic drugs on methaqualone-induced hypothermia

W O Boggan et al. Res Commun Chem Pathol Pharmacol. 1977 Apr.

Abstract

Methaqualone (75 mg/kg) produced a significant decrease in the rectal temperature of mice. This effect was antagonized by parachlorophenylalanine and potentiated by Lilly 110140. These compounds also decreased and increased respectively the circulating concentration of methaqualone.

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