Effects of serotonergic drugs on methaqualone-induced hypothermia
- PMID: 140451
Effects of serotonergic drugs on methaqualone-induced hypothermia
Abstract
Methaqualone (75 mg/kg) produced a significant decrease in the rectal temperature of mice. This effect was antagonized by parachlorophenylalanine and potentiated by Lilly 110140. These compounds also decreased and increased respectively the circulating concentration of methaqualone.
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