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. 1992 Nov;66(11):6813-8.
doi: 10.1128/JVI.66.11.6813-6818.1992.

Transcription of human respiratory syncytial virus genome RNA in vitro: requirement of cellular factor(s)

S Barik  1
Affiliations

Transcription of human respiratory syncytial virus genome RNA in vitro: requirement of cellular factor(s)

S Barik. J Virol. 1992 Nov.

Abstract

Extracts made from human respiratory syncytial virus (RSV)-infected Hep-2 cells synthesized mRNAs encoded by all known viral genes. In contrast, RSV ribonucleoproteins purified from infected cells failed to transcribe in vitro; transcription was restored by addition of a cytoplasmic extract of uninfected Hep-2 cells, demonstrating that a cellular factor(s) has a role in RSV gene expression. Quantitation of the individual gene mRNAs transcribed in vitro revealed polarity of transcription of the genome.

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References

    1. J Virol. 1979 Apr;30(1):108-15 - PubMed
    1. Infect Immun. 1982 Jul;37(1):243-9 - PubMed
    1. Virology. 1992 Jun;188(2):417-28 - PubMed
    1. J Virol. 1991 Jun;65(6):3268-75 - PubMed
    1. J Gen Virol. 1990 Apr;71 ( Pt 4):775-83 - PubMed

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