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. 1963 Sep;11(5):423-6.
doi: 10.1128/am.11.5.423-426.1963.

BACTERIAL VACCINE IN MULTIDOSE TABLET FORM FOR PARENTERAL USE

S BERMAN, J P LOWENTHAL, E W GROGAN, P L ALTIERI, A S BENENSON

BACTERIAL VACCINE IN MULTIDOSE TABLET FORM FOR PARENTERAL USE

S BERMAN et al. Appl Microbiol. 1963 Sep.

Abstract

Dried typhoid vaccines were prepared by freeze-drying of heat-inactivated phenolized-cell suspensions and by an acetone-killed and dried technique. Portions of the dried powder obtained by each method were compressed into tablets. Tests with the products showed that drying and making of tablets did not affect the ability of the vaccines to protect mice or elicit antibodies in rabbits.

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References

    1. Proc Soc Exp Biol Med. 1952 May;80(1):55-8 - PubMed
    1. Am J Hyg. 1953 Sep;58(2):148-64 - PubMed

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