Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1963 Oct;86(4):872-9.
doi: 10.1128/jb.86.4.872-879.1963.

EXPERIMENTAL SALMONELLOSIS. III. NEW TOXIC FRACTION (L) OBTAINED FROM SALMONELLA ENTERITIDIS AND ITS IMMUNOLOGICAL PROPERTIES

M KAWAKAMI, N OSAWA, S MITSUHASHI

EXPERIMENTAL SALMONELLOSIS. III. NEW TOXIC FRACTION (L) OBTAINED FROM SALMONELLA ENTERITIDIS AND ITS IMMUNOLOGICAL PROPERTIES

M KAWAKAMI et al. J Bacteriol. 1963 Oct.

Abstract

Kawakami, Masaya (Gunma University, Maebashi, Japan), Nobutaka Osawa, and Susumu Mitsuhashi. Experimental salmonellosis. III. New toxic fraction (L) obtained from Salmonella enteritidis and its immunological properties. J. Bacteriol. 86:872-879. 1963.-A method is described for the purification of the heat-labile toxins of a fully virulent strain, 116-54, of Salmonella enteritidis by ion-exchange chromatography. One component of the heat-labile toxin (L) was homogeneous, as evidenced by the results of the ultracentrifugal analysis and agar gel diffusion test. The mouse ld(50) was 1.3 mug, and chemical studies indicated that this toxin was a simple protein in nature. It was also evidenced by chemical and immunological tests that this toxin differs from the O antigen (lipopolysaccharide-protein complex).

PubMed Disclaimer

References

    1. Z Hyg Infektionskr. 1953;136(2):158-62 - PubMed
    1. Br J Exp Pathol. 1953 Apr;34(2):202-16 - PubMed
    1. J Immunol. 1952 Aug;69(2):135-42 - PubMed
    1. Science. 1948 Mar 5;107(2775):254-5 - PubMed
    1. Biochem J. 1937 Nov;31(11):2003-21 - PubMed