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. 1963 Nov 15;142(3594):972-3.
doi: 10.1126/science.142.3594.972.

LIPOPROTEIN MOVEMENT THROUGH CANINE AORTIC WALL

L E DUNCAN Jr, K BUCK, A LYNCH

LIPOPROTEIN MOVEMENT THROUGH CANINE AORTIC WALL

L E DUNCAN Jr et al. Science. .

Abstract

Low-density (1.019 to 1.063) lipoprotein labeled with radioiodine enters the inner layer of the canine aortic wall directly from the aortic lumen. Its rate of entry is greatest in the proximal aorta and decreases progressively down the length of the aorta. A similar gradient was observed previously for the accumulation of cholesterol early in experimental atherosclerosis.

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