Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1992 Oct 1;359(6394):380-7.
doi: 10.1038/359380a0.

Continuum of overlapping clones spanning the entire human chromosome 21q

I Chumakov  1 , P Rigault, S Guillou, P Ougen, A Billaut, G Guasconi, P Gervy, I LeGall, P Soularue, L Grinas, et al.
Affiliations
Comparative Study

Continuum of overlapping clones spanning the entire human chromosome 21q

I Chumakov et al. Nature. .

Abstract

A continuous array of overlapping clones covering the entire human chromosome 21q was constructed from human yeast artificial chromosome libraries using sequence-tagged sites as landmarks specifically detected by polymerase chain reaction. The yeast artificial chromosome contiguous unit starts with pericentromeric and ends with subtelomeric loci of 21q. The resulting order of sequence-tagged sites is consistent with other physical and genetic mapping data. This set of overlapping clones will promote our knowledge of the structure of this chromosome and the function of its genes.

PubMed Disclaimer

Comment in

  • Gene patents.
    [No authors listed] [No authors listed] Nature. 1992 Oct 1;359(6394):348. doi: 10.1038/359348a0. Nature. 1992. PMID: 1406940 No abstract available.
  • Human Genome Project: Mapping the way ahead.
    Little P. Little P. Nature. 1992 Oct 1;359(6394):367-8. doi: 10.1038/359367a0. Nature. 1992. PMID: 1406946 No abstract available.

Publication types

Substances

LinkOut - more resources