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. 1963 Nov 29;142(3596):1191-2.
doi: 10.1126/science.142.3596.1191.

AFLATOXIN B2: CHEMICAL IDENTITY AND BIOLOGICAL ACTIVITY

S B CHANG, M M ABDEL-KADER, E L WICK, G N WOGAN

AFLATOXIN B2: CHEMICAL IDENTITY AND BIOLOGICAL ACTIVITY

S B CHANG et al. Science. .

Abstract

Aflatoxin B(2), a blue-fluorescent metabolite of Aspergillus flavus, was isolated from cultures grown on crushed wheat. Chemical structure of the compound was elucidated as dihydroaflatoxin B(1). Biological activity was determined in day-old male white Pekin ducklings. The criteria of activity were reduction in growth and liver size and the extent of bile-duct hyperplasia.

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