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Case Reports
. 1992 Sep;74(3):343-7.
doi: 10.1016/0030-4220(92)90073-y.

B-cell lymphoma presenting as a midfacial necrotizing lesion

W G Maxymiw  1 , B J Patterson, R E Wood, J M Meharchand, A J Munro, I G'orska-Flipot
Affiliations
Case Reports

B-cell lymphoma presenting as a midfacial necrotizing lesion

W G Maxymiw et al. Oral Surg Oral Med Oral Pathol. 1992 Sep.

Abstract

A case of midfacial necrotizing lesion (midline nonhealing granuloma) is reported. Paraffin- and frozen-section immunocytochemistry suggested a tumor of B-cell lineage and was confirmed by Southern blot analysis that disclosed an immunoglobulin heavy chain gene rearrangement with no evidence of T-cell receptor genetic aberration. The tumor was of B-cell lineage despite the tumor site and the angiocentric pattern, which are typically seen with peripheral T cell lymphoma with this presentation.

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