Case Reports
Recombinant erythropoietin as treatment for the late hyporegenerative anemia of Rh hemolytic disease
Affiliations
- PMID: 1408538
Item in Clipboard
Case Reports
Recombinant erythropoietin as treatment for the late hyporegenerative anemia of Rh hemolytic disease
Pediatrics.
1992 Nov.
Abstract
Infants with Rh hemolytic disease can develop a "late" anemia characterized by low serum concentrations of erythropoietin but erythroid progenitors that remain highly erythropoietin-responsive. Erythropoietin administration was evaluated in two patients as an alternative to transfusion. Reticulocyte counts increased after 5 days of treatment, and hematocrits increased after 10 days. Neither patient received erythrocyte transfusions following erythropoietin therapy.
Similar articles
-
Management of late anemia in Rhesus hemolytic disease: use of recombinant human erythropoietin (a pilot study).Pediatr Res. 1996 May;39(5):831-4. doi: 10.1203/00006450-199605000-00015. Pediatr Res. 1996. PMID: 8726237 Clinical Trial.
-
Erythropoietin as treatment for late hyporegenerative anemia in neonates with Rh hemolytic disease after in utero exchange transfusion.Fetal Diagn Ther. 2002 Jan-Feb;17(1):22-4. doi: 10.1159/000048000. Fetal Diagn Ther. 2002. PMID: 11803211
-
The effectiveness of recombinant human erythropoietin (EPO) treatment in a neonate with hyporegenerative anemia following Rh isoimmunization in spite of normal serum Epo level.Pediatr Hematol Oncol. 2011 Nov;28(8):721-2. doi: 10.3109/08880018.2011.599051. Epub 2011 Aug 29. Pediatr Hematol Oncol. 2011. PMID: 21875319 No abstract available.
-
Recombinant human erythropoietin treatment of anemic cancer patients.Cancer Pract. 1996 Jul-Aug;4(4):180-4. Cancer Pract. 1996. PMID: 8900758 Review.
-
Benefits and costs of recombinant human erythropoietin for end-stage renal failure: a review. Benefits and costs of erythropoietin.Int J Technol Assess Health Care. 1993 Fall;9(4):490-504. doi: 10.1017/s0266462300005419. Int J Technol Assess Health Care. 1993. PMID: 8288425 Review.
Cited by
-
Erythrokinetic mechanism(s) causing the "late anemia" of hemolytic disease of the fetus and newborn.J Perinatol. 2024 Jun;44(6):916-919. doi: 10.1038/s41372-024-01872-z. Epub 2024 Jan 12. J Perinatol. 2024. PMID: 38216678 Review.
-
Haemolytic disease of newborn.Indian J Pediatr. 2001 Feb;68(2):167-72. doi: 10.1007/BF02722039. Indian J Pediatr. 2001. PMID: 11284186 Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Medical