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Case Reports
. 1992 Nov;90(5):678-80.

Recombinant erythropoietin as treatment for the late hyporegenerative anemia of Rh hemolytic disease

R K Ohls  1 , P E Wirkus, R D Christensen
Affiliations
  • PMID: 1408538
Case Reports

Recombinant erythropoietin as treatment for the late hyporegenerative anemia of Rh hemolytic disease

R K Ohls et al. Pediatrics. 1992 Nov.

Abstract

Infants with Rh hemolytic disease can develop a "late" anemia characterized by low serum concentrations of erythropoietin but erythroid progenitors that remain highly erythropoietin-responsive. Erythropoietin administration was evaluated in two patients as an alternative to transfusion. Reticulocyte counts increased after 5 days of treatment, and hematocrits increased after 10 days. Neither patient received erythrocyte transfusions following erythropoietin therapy.

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