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. 1963 Dec:54:900-11.

EXTRACORPOREAL PERFUSION FOR OBTAINING POSTMORTEM HOMOGRAFTS

T L MARCHIORO, R T HUNTLEY, W R WADDELL, T E STARZL

EXTRACORPOREAL PERFUSION FOR OBTAINING POSTMORTEM HOMOGRAFTS

T L MARCHIORO et al. Surgery. 1963 Dec.
No abstract available

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Figures

Fig. 1
Fig. 1
Technique of extracorporeal cadaver perfusion.
Fig. 2
Fig. 2
Cooling curves obtained during cadaver perfusion for a liver homograft. Note the rapid response of liver temperature to changes in perfusate temperature.
Fig. 3
Fig. 3
BUN level after renal homografting. Note the acute azotemia with the homograft perfused for 10½ hours. Early azotemia is minimal in the animal receiving a kidney perfused for 1¼ hours.
Fig. 4
Fig. 4
Patterns of injury in dogs observed following transplantation of a perfused hepatic homograft, and of a liver obtained after sacrifice of a living donor. Total time from death to reimplantation for the perfused organ was 140 minutes as compared to 55 minutes for the graft transplanted immediately after sacrifice (acute transplant).
Fig. 5
Fig. 5
Typical injury observed in livers perfused for more than 2 hours. Note the marked centrilobular congestion and parenchymal necrosis. (×32.)
Fig. 6
Fig. 6
A, Appearance of homografted cadaveric left kidney 24 days after transplantation. B, Cadaveric contralateral kidney immediately after cessation of perfusion. (×32.)
Fig. 7
Fig. 7
A, Homografted cadaveric right kidney removed 12 days after transplantation. Note rejection. B, Contralateral donor kidney obtained at conclusion of perfusion. (×32.)
Fig. 8
Fig. 8
Photomicrograph of first clinical hepatic homograft. The patient died on the operating table. Note advanced hepatic cell necrosis. (×32.)
Fig. 9
Fig. 9
Photomicrograph of liver from the second clinical hepatic transplant, obtained at autopsy 22 days after transplantation. Note preservation of hepatic architecture. Moderate periportal fibrosis and bile stasis are present. (×32.)
See this image and copyright information in PMC

References

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    1. Goodwin WE, Kaufman JJ, Mims MM, Turner RD, Glassock R, Goldman R, Maxwell MM. Human renal transplantation. I. Clinical experiences with 6 cases of renal transplantation. J Urol. 1963;89:13. - PubMed
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    1. Humphries AL, Jr, Russell R, Ostofin J, Goodrich SM, Moretz WH. Successful reimplantation of dog kidney after 24 hour storage. S Forum. 1962;13:380. - PubMed

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