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. 1964 Feb 21;143(3608):813-4.
doi: 10.1126/science.143.3608.813.

LYMPHOCYTE INTERACTION: A POTENTIAL HISTOCOMPATIBILITY TEST IN VITRO

LYMPHOCYTE INTERACTION: A POTENTIAL HISTOCOMPATIBILITY TEST IN VITRO

F BACH et al. Science. .

Abstract

Lymphocytes from two unrelated individuals, cultured together in the same tube, undergo morphological transformation to large cells and divide. Both of these parameters may be estimated quantitatively. There is a correlation between the degree of this response and the degree of cross-reactivity of grafts from the two individuals placed on a third unrelated recipient.

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