Comparative Study
[The effect of ionizing radiation at superhigh doses on the processes of dopamine release and reuptake by nerve endings in different sections of the brain]
[Article in
Russian]
- PMID: 1410293
Item in Clipboard
Comparative Study
[The effect of ionizing radiation at superhigh doses on the processes of dopamine release and reuptake by nerve endings in different sections of the brain]
[Article in
Russian]
Radiobiologiia.
1992 Jul-Aug.
Abstract
Rats exposed to fast 24 MeV electrons (100 Gy) at the state of early transient incapacity (ETI) exhibited active release and reuptake of dopamine in nerve terminals of the striatum. No changes in the indices under study were found in rats exposed to 25 Gy radiation that did not cause the ETI development. The in vitro irradiation of the isolated synaptosomes (100 Gy) inhibited dopamine reuptake and increased the number of sites of 3H-spiperone binding to D2-receptors in a membrane fraction isolated from the striatum.
Similar articles
-
Glial cell line-derived neurotrophic factor (GDNF) enhances dopamine release from striatal nerve endings in an adenosine A2A receptor-dependent manner.Brain Res. 2006 Oct 3;1113(1):129-36. doi: 10.1016/j.brainres.2006.07.025. Epub 2006 Aug 28. Brain Res. 2006. PMID: 16935271
-
Covalent interaction of [3H]-dopamine with rat brain proteins in vivo and with the dopamine-reuptake site of nerve endings in vitro.J Neurosci Res. 1981;6(4):539-52. doi: 10.1002/jnr.490060410. J Neurosci Res. 1981. PMID: 7299853
-
Distinctions between ligand-binding sites for [3H]dopamine and D2 dopaminergic receptors characterized with [3H]spiroperidol.Mol Pharmacol. 1984 Nov;26(3):439-51. Mol Pharmacol. 1984. PMID: 6238230
-
Distribution of neurotensin receptors in mammalian brain. What it is telling us about its interactions with other neurotransmitter systems.Ann N Y Acad Sci. 1992;668:109-19. doi: 10.1111/j.1749-6632.1992.tb27343.x. Ann N Y Acad Sci. 1992. PMID: 1361109 Review. No abstract available.
-
Presynaptic regulation of dopamine release. Implications for the functional organization of the basal ganglia.Ann N Y Acad Sci. 1990;604:17-22. doi: 10.1111/j.1749-6632.1990.tb31979.x. Ann N Y Acad Sci. 1990. PMID: 2171393 Review. No abstract available.