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. 1964 May 29;144(3622):1141-7.
doi: 10.1126/science.144.3622.1141.

GAMMA-GLOBULIN AFFINITY FOR NORMAL HUMAN TISSUE OF THE CENTRAL NERVOUS SYSTEM

C D ALLERAND, M D YAHR

GAMMA-GLOBULIN AFFINITY FOR NORMAL HUMAN TISSUE OF THE CENTRAL NERVOUS SYSTEM

C D ALLERAND et al. Science. .

Abstract

Immunofluorescent staining of the serum and cerebrospinal fluid of patients with and without neurological disease demonstrates an affinity of the gamma-globulin fraction for glial cells and myelin sheaths in normal human nervous tissue. This affinity appears to be specific for the 7S gamma-globulin fraction and is not seen with the other major protein fractions of serum and cerebrospinal fluid or with the fluorescein conjugated antisera alone.

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