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Review
. 1992 Oct;304(4):261-7.
doi: 10.1097/00000441-199210000-00008.

Loxoscelism

J M Futrell  1
Affiliations
Review

Loxoscelism

J M Futrell. Am J Med Sci. 1992 Oct.

Abstract

Loxoscelism, or envenomation by the brown recluse spider, may result in necrotic lesions and systemic reactions, including hemolytic anemia. Histologically, it resembles a cutaneous Arthus reaction. The reaction mechanism involves interactions between complement, neutrophils, and the clotting system. It is best treated with analgesics, avoidance of early surgical debridement, and oral dapsone.

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