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. 1964 Apr;21(1):105-14.
doi: 10.1083/jcb.21.1.105.

THE FATE OF DNA-CONTAINING PARTICLES PHAGOCYTIZED BY MAMMALIAN CELLS

K BENSCH, G GORDON, L MILLER

THE FATE OF DNA-CONTAINING PARTICLES PHAGOCYTIZED BY MAMMALIAN CELLS

K BENSCH et al. J Cell Biol. 1964 Apr.

Abstract

Particulate DNA protein coacervates were digested immediately after being phagocytized by L strain fibroblasts in suspension culture. Enlargement of the phagocytotic vacuoles occurred simultaneously with a loss of the electron opacity of the phagocytized particles. Cytochemical reactions positive for non-specific esterase, acid phosphatase, and nucleoside phosphatase in the phagocytotic vacuoles provided additional evidence for the probability of complete hydrolysis of the phagocytized nucleoprotein.

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References

    1. J Biophys Biochem Cytol. 1961 Feb;9:409-14 - PubMed
    1. Science. 1961 Feb 10;133(3450):381-2 - PubMed
    1. J Histochem Cytochem. 1961 May;9:325-39 - PubMed
    1. Br J Exp Pathol. 1958 Jun;39(3):292-9 - PubMed
    1. Exp Cell Res. 1963 Aug;31:440-3 - PubMed