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. 1964 May;17(3):225-30.
doi: 10.1136/jcp.17.3.225.

A COMPARISON OF A FLUORESCENT ANTIBODY TECHNIQUE WITH A CULTURAL METHOD IN THE DETECTION OF INFECTIONS WITH SHIGELLA SONNEI

C E TAYLOR, G V HEIMER, D J LEA, A J TOMLINSON

A COMPARISON OF A FLUORESCENT ANTIBODY TECHNIQUE WITH A CULTURAL METHOD IN THE DETECTION OF INFECTIONS WITH SHIGELLA SONNEI

C E TAYLOR et al. J Clin Pathol. 1964 May.

Abstract

A comparison has been made of a fluorescent antibody technique with a cultural method for the detection of Sh. sonnei in faeces. The two methods were in agreement in 73% of the 394 specimens examined; 57 (14.5%) speciments were positive by culture only; 52 (13.2%) specimens gave positive results by fluorescence microscopy which were not confirmed by culture. Most of the latter are thought to be ;false positive' results.The value and usefulness of fluorescence microscopy in the diagnosis of Sonne dysentery is discussed.

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