Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1992 Jun;36(6):1322-4.
doi: 10.1128/AAC.36.6.1322.

Antimycoplasmal activities of new quinolones, tetracyclines, and macrolides against Mycoplasma pneumoniae

S Arai  1 , Y Gohara, K Kuwano, T Kawashima
Affiliations

Antimycoplasmal activities of new quinolones, tetracyclines, and macrolides against Mycoplasma pneumoniae

S Arai et al. Antimicrob Agents Chemother. 1992 Jun.

Abstract

Fifty strains of Mycoplasma pneumoniae were tested for susceptibility to new quinolones, tetracyclines, and macrolides. Temafloxacin, ofloxacin, and ciprofloxacin possessed the most mycoplasmacidal activity against these organisms. The MBC for 50% of the strains (MBC50)-to-MIC50 ratio for each of these drugs was 4. The MBC50-to-MIC50 ratios for the tetracyclines and macrolides were markedly higher, within a range of 32 to 2,000. On the basis of these results, temafloxacin and ofloxacin might be promising antimicrobial agents for the treatment of mycoplasmal infection.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Antimicrob Agents Chemother. 1976 Dec;10(6):899-901 - PubMed
    1. Antimicrob Agents Chemother. 1988 Oct;32(10):1500-2 - PubMed
    1. Rev Infect Dis. 1986 Jul-Aug;8 Suppl 3:S279-91 - PubMed
    1. J Pediatr. 1970 Mar;76(3):438-43 - PubMed
    1. J Clin Invest. 1983 Mar;71(3):411-9 - PubMed

Publication types

MeSH terms