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. 1964 Jun 12;144(3624):1344-6.
doi: 10.1126/science.144.3624.1344.

ANTIBODIES TO BRADYKININ AND ANGIOTENSIN: A USE OF CARBODIIMIDES IN IMMUNOLOGY

T L GOODFRIEND, L LEVINE, G D FASMAN

ANTIBODIES TO BRADYKININ AND ANGIOTENSIN: A USE OF CARBODIIMIDES IN IMMUNOLOGY

T L GOODFRIEND et al. Science. .

Abstract

Antibodies to bradykinin and angiotensin have been produced in rabbits by the use of conjugates containing albumin and the hapten, covalently bound. The use of water-soluble carbodiimide reagents provided an easy and rapid method of synthesis of the antigenic conjugates.

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