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. 1964 Jul 10;145(3628):157-9.
doi: 10.1126/science.145.3628.157.

IDENTIFICTION OF ACETYLCHOLINE IN SYMPATHETIC GANGLIA BY CHEMICAL AND PHYSICAL METHODS

A J FRIESEN, J W KEMP, D M WOODBURY

IDENTIFICTION OF ACETYLCHOLINE IN SYMPATHETIC GANGLIA BY CHEMICAL AND PHYSICAL METHODS

A J FRIESEN et al. Science. .

Abstract

Extracts of sympathetic ganglionic chains contain a substance which behaves like acetylcholine biologically, chromatographically, and electrophoretically. The melting point of the tetrachloroaurate salt of this substance is identical to that of acetylcholine tetrachloroaurate. No other choline esters have been detected in these extracts. Perfusion of sympathetic ganglia with C(14)-choline indicates that C(14)-acetylcholine is released.

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