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. 1964 Sep 25;145(3639):1439.
doi: 10.1126/science.145.3639.1439.

MYCOTOXINS: AFLATOXIN ISOLATED FROM PENICILLIUM PUBERULUM

F A HODGES, J R ZUST, H R SMITH, A A NELSON, B H ARMBRECHT, A D CAMPBELL

MYCOTOXINS: AFLATOXIN ISOLATED FROM PENICILLIUM PUBERULUM

F A HODGES et al. Science. .

Abstract

Penicillium puberulum Bainer was found growing on a sample of moldy peanuts. It also grows on shredded wheat, potatoes, and laboratory culture media such as wort, potato dextrose, and Sabouraud agars, and synthesizes aflatoxin on these substrates. Thin-layer chromatograms of the chloroform-soluble toxin produced by the mold when grown on shredded wheat show fluorescent bands with R(F) values identical with those of the fractions B(1), B(2), G(1), and G(2) of the toxin produced by Aspergillus flavus. This extract produces typical bile duct proliferation type of liver damage in 2-to 3-day-old Peking white ducklings.

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