Diseases associated with HTLV-I: virus, IL-2 receptor dysregulation and redox regulation
- PMID: 1418377
- DOI: 10.1016/0167-5699(92)90091-K
Diseases associated with HTLV-I: virus, IL-2 receptor dysregulation and redox regulation
Abstract
HTLV-I, the etiological agent in adult T-cell leukemia, has also been strongly implicated in a number of non-neoplastic T-cell-associated diseases. Here, Junji Yodoi and Takashi Uchiyama review these associations and focus on the emerging concepts of IL-2R dysregulation and redox regulation by adult T-cell leukemia-derived factor in the pathogenesis of HTLV-I-related diseases.
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