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. 1964 Oct 16;146(3642):401-3.
doi: 10.1126/science.146.3642.401.

VALENCE AND AFFINITY OF EQUINE NONPRECIPITATING ANTIBODY TO A HAPTENIC GROUP

N R KLIMAN, J H ROCKEY, F KARUSH

VALENCE AND AFFINITY OF EQUINE NONPRECIPITATING ANTIBODY TO A HAPTENIC GROUP

N R KLIMAN et al. Science. .

Abstract

A nonprecipitable antibody to a haptenic group has been purified from equine serum. It is a 7S beta2delta immunoglobulin with high affinity for the specific hapten and two binding sites per antibody molecule. These results rule out univalence and low affinity as explanations of the nonprecipitability of this antibody.

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