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Review
. 1992 Aug;4(4):696-702.
doi: 10.1016/0955-0674(92)90091-p.

Sodium cotransport proteins

E M Wright  1 , K M Hager, E Turk
Affiliations
Review

Sodium cotransport proteins

E M Wright et al. Curr Opin Cell Biol. 1992 Aug.

Abstract

Significant advances have been made in elucidating the structure of Na+ cotransport proteins. Some fifteen of these low-abundance proteins have been cloned, sequenced and functionally expressed. They are members of the 12 membrane-spanning superfamily and they segregate into two groups, the Na+/glucose (SGLT1) and Na+/Cl-/GABA (GAT-1) families. SGLT1 transporters are expressed in bacteria and animal cells, while GAT-1 transporters are mostly expressed in the brain. None have yet been found in plants.

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