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Comparative Study
. 1992 Autumn;5(3):157-61.
doi: 10.1007/BF01061322.

Mutagenic activity of copper(II) chromate and dichromate complexes with polypyridines

K Szyba  1 , M C Golonka, K Gasiorowski, J Urban
Affiliations
Comparative Study

Mutagenic activity of copper(II) chromate and dichromate complexes with polypyridines

K Szyba et al. Biometals. 1992 Autumn.

Abstract

Copper(II) chromate and dichromate complexes with 2,2'-bipyridyl and 1,10-phenathroline were tested for their mutagenic activity in the standard Ames test. All of six tested complexes exhibited markedly lower mutagenic activity than the reference compounds--potassium dichromate and sodium chromate. The blockage of Cr(VI) reduction capability in the presence of the complex Cu2+ ion and the competition between copper and chromium ions in the interaction with cellular components are discussed in the light of the results of our previous chemical study.

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