Classical Article
Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells. 1978
- PMID: 1422048
Item in Clipboard
Classical Article
Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells. 1978
Biotechnology.
1992.
No abstract available
Similar articles
-
Selective expression of methotrexate-resistant dihydrofolate reductase (DHFR) activity in mice transduced with DHFR retrovirus and administered methotrexate.J Pharmacol Exp Ther. 1993 Nov;267(2):989-96. J Pharmacol Exp Ther. 1993. PMID: 8246174
-
Gene amplification and drug resistance in mammalian cells.Natl Cancer Inst Monogr. 1982;60:79-86. Natl Cancer Inst Monogr. 1982. PMID: 7121575
-
Stimulation of methotrexate resistance and dihydrofolate reductase gene amplification by c-myc.Oncogene. 1991 Aug;6(8):1453-7. Oncogene. 1991. PMID: 1886715
-
Drug-resistant dihydrofolate reductases: generation, expression and therapeutic application.Bone Marrow Transplant. 1996 Dec;18 Suppl 3:S50-4. Bone Marrow Transplant. 1996. PMID: 8971409 Review.
-
In vitro mutations in dihydrofolate reductase that confer resistance to methotrexate: potential for clinical application.Hum Mutat. 1998;11(4):259-63. doi: 10.1002/(SICI)1098-1004(1998)11:4<259::AID-HUMU1>3.0.CO;2-W. Hum Mutat. 1998. PMID: 9554740 Review.
Cited by
-
The biogenesis and roles of extrachromosomal oncogene involved in carcinogenesis and evolution.Am J Cancer Res. 2020 Nov 1;10(11):3532-3550. eCollection 2020. Am J Cancer Res. 2020. PMID: 33294253 Free PMC article. Review.
-
The challenge of drug resistance in cancer treatment: a current overview.Clin Exp Metastasis. 2018 Apr;35(4):309-318. doi: 10.1007/s10585-018-9903-0. Epub 2018 May 24. Clin Exp Metastasis. 2018. PMID: 29799080 Review.
-
Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges.Cancer Discov. 2022 Apr 1;12(4):1046-1069. doi: 10.1158/2159-8290.CD-20-0936. Cancer Discov. 2022. PMID: 34930786 Free PMC article.