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Review
. 1992 Oct;2(5):582-5.
doi: 10.1016/0959-4388(92)90022-d.

Reconstituting animals from immortal precursors

Affiliations
Review

Reconstituting animals from immortal precursors

R McKay. Curr Opin Neurobiol. 1992 Oct.

Abstract

Several recent experiments have shown that immortal neural and muscle cells retain the specific temporal and spatial properties of their precursor cells in the animal. In addition, the immortal cells retain the ability to differentiate in vitro and, after transplantation, in vivo. The results of these experiments suggest that the use of precursor cell lines may lead to powerful approaches for understanding the mechanisms that generate the ordered distribution of cell types in mammals.

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