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. 1977 May 16;223(3):265-70.
doi: 10.1007/BF00342343.

The cerebrospinal fluid choline levels in patients with Huntington's chorea. Negative effect of haloperidol treatment

S Consolo, H Ladinsky, S Bianchi, T Caraceni

The cerebrospinal fluid choline levels in patients with Huntington's chorea. Negative effect of haloperidol treatment

S Consolo et al. Arch Psychiatr Nervenkr (1970). .

Abstract

Lumbar cerebrospinal fluid (CSF) choline (CH) levels were measured in patients with Huntington's chorea (n = 14). This group was found not to differ significantly from normal controls (n = 13). The values for lumbar CSF Ch levels in the normal subjects were comparable with previously reported values. Of the choreic patients, seven were put on haloperidol treatment (4--6 mg daily). The CSF choline level remained unchanged with this treatment after 20 days. CSF cholinesterase activity was measured in the control and choreic group. The results were not significantly different.

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