[Genetic analysis of various behavioral and physiologic characteristics in hybrids between hypertensive and normotensive rats. Analysis of reciprocal differences]

Abstract

As a result of reciprocal crosses between the SHR rats (spontaneously hypertensive strain) and WKY rats (normotensive strain), two types each of the F1 and F2 hybrids and 4 types of backcrosses were obtained. Analysis of reciprocal differences carries out in these generations for a number of behavioral and physiological traits demonstrated linkage of an hereditary factor affecting expression of potassium appetite with the Y-chromosome. The maternal effect contrary to the action of chromosomal hereditary factors was established for locomotor activity in the peripheral zone of open field. This maternal effect was manifested in the F1 and F2 generations, but not in backcrosses.