doi: 10.1007/BF02918616.
Alcohol can inhibit effect of IL-4 on activated murine B cells
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- PMID: 1431420
- DOI: 10.1007/BF02918616
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Alcohol can inhibit effect of IL-4 on activated murine B cells
Immunol Res.
1992.
Abstract
Ethanol addition to B lymphocytes in vitro inhibits antigen-induced antibody secretion and antigen-induced cell proliferation. We tested the hypothesis that ethanol can inhibit the effect of interleukins on B-cell proliferation by adding ethanol to in vitro functional assays for IL-2 and IL-4. Ethanol does not inhibit IL-2-induced B-cell differentiation, but it does inhibit IL-4-induced B-cell proliferation and IL-4-induced Ig class switching.
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